Coronary perfusion pressure (CPP) is the pressure difference between the aortic diastolic pressure and the left ventricular end-diastolic pressure during the diastolic phase of the cardiac cycle. It represents the pressure gradient that drives the flow of oxygenated blood to the heart muscle (myocardium) through the coronary arteries.
The aortic pressure during diastole is an important determinant of coronary perfusion, as the coronary arteries receive blood flow primarily during diastole when the heart is relaxed and the coronary arteries are not compressed by the contracting myocardium.
The CPP is a critical factor in determining the supply of oxygen and nutrients to the heart muscle. A decrease in CPP can lead to inadequate coronary perfusion, which can result in myocardial ischemia, injury, and eventually, myocardial infarction (heart attack).
Maintaining an adequate CPP is crucial for the proper functioning of the heart and the prevention of coronary artery disease. In clinical settings, interventions such as medications, interventions, or lifestyle changes may be necessary to optimize CPP and ensure proper coronary perfusion.
Ne Demek sitesindeki bilgiler kullanıcılar vasıtasıyla veya otomatik oluşturulmuştur. Buradaki bilgilerin doğru olduğu garanti edilmez. Düzeltilmesi gereken bilgi olduğunu düşünüyorsanız bizimle iletişime geçiniz. Her türlü görüş, destek ve önerileriniz için iletisim@nedemek.page